September 15, 2020
Amsterdam University Medical Centers and AlphaBiomics initiate collaboration to validate IBD biologic therapy response predictor, RxSelexTM
The Amsterdam University Medical Centers (Amsterdam UMC) in the Netherlands and AlphaBiomics Ltd., a United Kingdom-based precision medicine company, have initiated a collboration to personalize care in patients suffering from inflammatory bowel disease (IBD).
IBD patient response to biologics therapy is highly variable, with some patients receiving long-term benefits, while others respond temporarily or not at all. At the same time, biologics therapy can be accompanied by significant side-effects. To predict which IBD patients will benefit from biologics therapy, AlphaBiomics has developed a non-invasive, stool microbiome-based diagnostic test (RxSelexTM).
To validate RxSelexTM, AlphaBiomics will collaborate with Professor Geert D’Haens and his team at the Amsterdam UMC Department of Gastroenterology who are world-renowned experts in the care of IBD patients and the rigorous evaluation of the efficacy and safety of IBD therapies.
IBD patients at Amsterdam UMC recruited to the study will be asked to collect a stool sample prior to starting biologics therapy and their therapy response will be carefully recorded over a period of 6 months. Individual patient response as
predicted by RxSelexTM from stool samples will be compared against the actual outcomes.
This 2-year project is funded by the UK National Institute for Health Research (NIHR). The project aims to carry out crucial steps needed to bring RxSelexTM to physicians and patients, such as the final development of the laboratory tests and computer programs, alignment with patient wishes and implementation in and adoption by healthcare systems.
April 9, 2020
AlphaBiomics wins award to validate its IBD biologic therapy response predictor, RxSelex
AlphaBiomics has been granted an Invention for Innovation Product Development Award to validate RxSelex, its microbiome-based predictive diagnostic for response to biologic therapy in patients experiencing inflammatory bowel disease (IBD). This 2-year program is funded by the National Institute for Health Research (NIHR). Working with renowned experts, AlphaBiomics will verify that the RxSelex machine learning algorithm correctly predicts biologic treatment response of patients in the United Kingdom and the Netherlands, and develop the laboratory tests and computer programs needed for RxSelex. In addition, AlphaBiomics will determine the value of RxSelex for patients and for the UK National Health Service (NHS). Patients will be involved throughout to advise and guide the research, based on their invaluable insights and experiences. These critical steps will place AlphaBiomics in a strong position to generate the evidence required to speed up RxSelex adoption by the NHS and healthcare systems globally, bringing relief to underserved patients experiencing IBD.
AlphaBiomics selected for Innovate UK and NIHR Investment Readiness Program
AlphaBiomics is among a small group of MedTech, Diagnostic, and Digital Health companies selected to participate in an Investment Readiness Program organised by the Knowledge Transfer Network (KTN) in collaboration with Innovate UK, the National Institute for Health and Research (NIHR), and the NHS England and NHS Improvement Small Business Research Initiative (SBRI). The program teaches theory and practice of what is expected when raising investment and how to put forward a strong proposition. At the end of the program, selected companies will present their opportunity to a room of investors.
March 12, 2020
AlphaBiomics attended advisory board meeting for the KTN Microbiome SIG
AlphaBiomics was among the select few companies to be invited to attend and present an advisory board meeting of the Knowledge Transfer Network (KTN) Microbiome Special Interest Group (SIG). The aim of SIG is to accelerate the commercialisation of microbiome-based products and services in the UK. AlphaBiomics CEO Anthony Williamson presented AlphaBiomics’ mission and project portfolio to an expert group from Academia, industry, and investors.
February 13-15, 2020
AlphaBiomics at the 15th Congress of ECCO
AlphaBiomics is attending the 2020 congress of the European Crohn’s and Colitis Organisation (ECCO) in Vienna. We are looking forward to hear the latest in IBD research and treatment and to catch up with old and meet new collaborators. Busy 3 days ahead!
February 5-6, 2020
AlphaBiomics at the 4th Microbiome Movement – Drug Development Summit Europe 2020
We will attend the fourth edition of the Microbiome Movement conference series in London. This year’s focus is on disease causation and clinical translation.
January 29-30, 2020
AlphaBiomics attended the 2020 Festival of Genomics & Biodata
The Festival of Genomics is the largest meeting in the UK dedicated to translational genomics. We were inspired by talks ranging from artificial intelligence and machine learning in translational medicine to patient and public involvement. It was also a great opportunity to connect with old and new collaborators.
June 3, 2019
AlphaBiomics featured as one of the 2019 residents of JLABS @ BE
AlphaBiomics is featured in this article by Labiotech.eu as one of seven companies who joined JLABS @ BE in 2019. It is the first JLABS incubator in Europe and located on the Janssen Pharmaceutica R&D Campus in Beerse, Belgium. JLABS will provide a stimulating, creative, scientific and commercial environment as well as an opportunity to network.
May 8-9, 2019
AlphaBiomics pitched at State of the Union event in Ghent, BE
AlphaBiomics was among four start-up companies to pitch at the 5th edition of the State of the Union event in Ghent, Belgium. This event was held the evening before the annual knowledge for growth conference which we also attended. Both gatherings are organised annually by flanders.bio, a life sciences cluster organisation based in Flanders, Belgium. Positive feedback on the pitch and great networking opportunities at both events led to many new contacts.
April 10-11, 2019
AlphaBiomics at the Diagnostics North East Conference 2019
AlphaBiomics has attended a Dx-focused workshop and conference organised by Diagnostics North East. We heard from experts in the Dx field and made valuable connections.
March 6-9, 2019
AlphaBiomics at the 14th Congress of ECCO
AlphaBiomics is attending the 2019 congress of the European Crohn’s and Colitis Organisation (ECCO) in Copenhagen. We are looking forward to hear the latest in IBD research and treatment and to catch up with old and meet new collaborators. Busy 3 days ahead!
February 5, 2019
AlphaBiomics wins award to advance its platform
AlphaBiomics has been awarded an Invention for Innovation (i4i) Connect grant to complete its pioneering microbiome analysis platform, ABFlow+. This project is funded by the National Institute for Health Research (NIHR) i4i Connect NIHR200405. Working with renowned experts, AlphaBiomics will develop and validate computationally and statistically robust toolkits for AI-based analysis of microbiome-derived data sets. The funds will also allow AlphaBiomics to perform health economic modelling for its precision medicine products and to engage relevant stakeholders including patients, healthcare professionals, and payors. This award enables AlphaBiomics to progress its discovery program and to advance its mission of bringing safer and more efficacious drug therapies to patients.
January 29-30, 2019
AlphaBiomics at the 3rd Microbiome Movement – Drug Development Summit Europe 2019
We just arrived in Paris to attend the third edition of the Microbiome Movement conference series. This year’s focus is on discovering, developing, and delivering the next generation of microbiome-based therapeutic and diagnostic candidates to market.
November 5, 2018
AlphaBiomics wins the European QuickFire Challenge of Johnson & Johnson Innovation
As the winner of the European Innovation QuickFire Challenge, AlphaBiomics will receive €100,000 in grant funding to further advance its solutions in human healthcare as well as a voucher for one year of residency at an available JLABS location. Read more at Johnson & Johnson Innovation.